Condition: POLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHY
rs104893998
in
LOC105375056;TREM2
gene and
POLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHY
PMID 12925681
2003 DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features.
rs121908402
in
TREM2;LOC105375056
gene and
POLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHY
PMID 15883308
2005 The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2.
PMID 18546367
2008 Mutations in TREM2 lead to pure early-onset dementia without bone cysts.
rs104894732
in
TYROBP
gene and
POLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHY
PMID 12370476
2002 Heterogeneity of presenile dementia with bone cysts (Nasu-Hakola disease): three genetic forms.
PMID 10888890
2000 Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.