Condition: PSORIASIS 2


rs146214639 in CARD14 gene and PSORIASIS 2 PMID 22521419 2012 Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.

PMID 26358359 2016 CARD14 alterations in Tunisian patients with psoriasis and further characterization in European cohorts.

PMID 27071417 2016 Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.

PMID 22521418 2012 PSORS2 is due to mutations in CARD14.

PMID 27113748 2016 The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes.