Condition: PSORIASIS 2
rs146214639 in
CARD14 gene and
PSORIASIS 2
PMID 22521419 2012 Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.
PMID 26358359 2016 CARD14 alterations in Tunisian patients with psoriasis and further characterization in European cohorts.
PMID 27071417 2016 Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.
PMID 22521418 2012 PSORS2 is due to mutations in CARD14.
PMID 27113748 2016 The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes.