Gene: CARD14
Alternate names for this Gene: BIMP2|CARMA2|PRP|PSORS2|PSS1
Gene Summary: This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants.
Gene is located in Chromosome: 17
Location in Chromosome : 17q25.3
Description of this Gene: caspase recruitment domain family member 14
Type of Gene: protein-coding