Condition: Thyroid carcinoma
rs11693806 in
DIRC3 gene and
Thyroid carcinoma
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.
PMID 23894154 2013 Genome-wide association study on differentiated thyroid cancer.
PMID 22267200 2012 After combining the results, three variants were shown to associate with thyroid cancer: rs966423 on 2q35 (OR = 1.34; P(combined) = 1.3 × 10(-9)), rs2439302 on 8p12 (OR = 1.36; P(combined) = 2.0 × 10(-9)) and rs116909374 on 14q13.3 (OR = 2.09; P(combined) = 4.6 × 10(-11)), a region previously reported to contain an uncorrelated variant conferring risk of thyroid cancer.
rs73227498 in
EPB41L4A gene and
Thyroid carcinoma
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.
rs1443434 in
FOXE1 gene and
Thyroid carcinoma
PMID 19198613 2009 Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
PMID 23894154 2013 Genome-wide association study on differentiated thyroid cancer.
rs368187 in
LOC105370452 gene and
Thyroid carcinoma
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.
rs7037324 in
LOC112268051 gene and
Thyroid carcinoma
PMID 25855579 2015 The association between the variation at the 9q22 locus near FOXE1 and thyroid cancer risk was consistent across all series, with several SNPs identified (rs7028661: OR = 1.64, p = 1.0 × 10(-22) , rs7037324: OR = 1.54, p = 1.2 × 10(-17) ).
rs6793295 in
LRRC34 gene and
Thyroid carcinoma
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.
rs2439302 in
NRG1 gene and
Thyroid carcinoma
PMID 22267200 2012 After combining the results, three variants were shown to associate with thyroid cancer: rs966423 on 2q35 (OR = 1.34; P(combined) = 1.3 × 10(-9)), rs2439302 on 8p12 (OR = 1.36; P(combined) = 2.0 × 10(-9)) and rs116909374 on 14q13.3 (OR = 2.09; P(combined) = 4.6 × 10(-11)), a region previously reported to contain an uncorrelated variant conferring risk of thyroid cancer.
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.
rs12129938 in
PCNX2 gene and
Thyroid carcinoma
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.
rs10759944 in
PTCSC2 gene and
Thyroid carcinoma
PMID 19198613 2009 Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
PMID 20350937 2010 The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.
PMID 23894154 2013 Genome-wide association study on differentiated thyroid cancer.
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.
PMID 30104761 2018 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
PMID 22267200 2012 Of those, rs965513 has previously been shown to associate with thyroid cancer.
PMID 25855579 2015 Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations.
rs1867277 in
PTCSC2;FOXE1 gene and
Thyroid carcinoma
PMID 20350937 2010 The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.
rs75076352 in
RET gene and
Thyroid carcinoma
PMID 16778204 2006 The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins.
PMID 11389085 2001 Nuclear factor-kappaB is constitutively active in C-cell carcinoma and required for RET-induced transformation.
PMID 23416954 2013 High penetrance of pheochromocytoma in multiple endocrine neoplasia 2 caused by germ line RET codon 634 mutation in Japanese patients.
rs2289261 in
SMAD3 gene and
Thyroid carcinoma
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.
rs10069690 in
TERT gene and
Thyroid carcinoma
PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.