Gene: PCNX2

Alternate names for this Gene: PCNXL2

Gene Summary: This gene contains coding mononucleotide repeats that are associated with tumors of high mcrosatellite instability (MSI-H). Defects in this gene are involved in the tumorigenesis of MSI-H colorectal carcinomas.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.2

Description of this Gene: pecanex 2

Type of Gene: protein-coding

rs2273673 in PCNX2 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs1159970 in PCNX2 gene and Brain Waves PMID 29947131 2018 Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity.

rs12027542 in PCNX2 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 21490949 2011 Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.

rs4649295 in PCNX2 gene and Differentiated Thyroid Gland Carcinoma PMID 28703219 2017 Genome-wide association and expression quantitative trait loci studies identify multiple susceptibility loci for thyroid cancer.

rs4649295 in PCNX2 gene and Papillary thyroid carcinoma PMID 28703219 2017 Genome-wide association and expression quantitative trait loci studies identify multiple susceptibility loci for thyroid cancer.

rs2273673 in PCNX2 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs12129938 in PCNX2 gene and Thyroid carcinoma PMID 28195142 2017 A genome-wide association study yields five novel thyroid cancer risk loci.