Gene: ARAP2
Alternate names for this Gene: CENTD1|PARX
Gene Summary: The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.
Gene is located in Chromosome: 4
Location in Chromosome : 4p14
Description of this Gene: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Type of Gene: protein-coding