rs4879628 in APTX gene and Amyotrophic Lateral Sclerosis

PMID 26580837 2016 A genome-wide association study on amyotrophic lateral sclerosis in the Taiwanese Han population.

rs12651329 in ARAP2 gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

rs2364403 in ARHGEF2 gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

rs10143310 in ATXN3 gene and Amyotrophic Lateral Sclerosis

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

rs10438933 in B4GALT6 gene and Amyotrophic Lateral Sclerosis

PMID 19451621 2009 Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis.

rs10122902 in C9orf72 gene and Amyotrophic Lateral Sclerosis

PMID 20801717 2010 Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.

PMID 23587638 2013 Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.

PMID 20801718 2010 Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study.

rs3849942 in C9orf72;LOC107987057 gene and Amyotrophic Lateral Sclerosis

PMID 20801718 2010 The other was detected in a 232 kb block of linkage disequilibrium (rs3849942, p=9·11×10(-11)) in a region of chromosome 9p that was previously identified in linkage studies of families with ALS.

PMID 22959728 2013 Eight genomic regions provided evidence of association with ALS, including 9p21.2 (rs3849942, odds ratio [OR] = 1.21; p = 4.41 × 10(-7)), 17p11.2 (rs7477, OR = 1.30; p = 2.89 × 10(-7)), and 19p13 (rs12608932, OR = 1.37, p = 1.29 × 10(-7)).

PMID 20801717 2010 In this analysis, two single nucleotide polymorphisms in a locus on chromosome 9p21.2 were associated with ALS: rs3849942 (p=2·22×10(-6); odds ratio [OR] 1·39, 95% CI 1·21-1·59) and rs2814707 (p=3·32×10(-6); 1·38, 1·20-1·58).

PMID 19734901 2009 Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.

PMID 23587638 2013 Genome-wide association testing was performed first using all samples, and then restricting the analysis to samples not carrying the mutation. rs3849942 and rs903603 were strongly associated with ALS when all samples were included (rs3849942, p = [3 × 2] × 10(-6), rank 7/442,057; rs903603, p = [7 × 6] × 10(-8), rank 2/442,057).

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

PMID 24931836 2014 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.

PMID 27455348 2016 Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

rs75087725 in CFAP410 gene and Amyotrophic Lateral Sclerosis

PMID 27455348 2016 Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

rs1320900 in CPNE4 gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

rs10260404 in DPP6 gene and Amyotrophic Lateral Sclerosis

PMID 18084291 2008 Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis.

rs7961471 in GRIP1 gene and Amyotrophic Lateral Sclerosis

PMID 23624525 2013 Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.

rs3806873 in ICE1 gene and Amyotrophic Lateral Sclerosis

PMID 23587638 2013 Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.

rs1008459 in KIAA0040 gene and Amyotrophic Lateral Sclerosis

PMID 17362836 2007 Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.

rs8056742 in KIAA0513 gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

rs113247976 in KIF5A gene and Amyotrophic Lateral Sclerosis

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

rs1541160 in KIFAP3 gene and Amyotrophic Lateral Sclerosis

PMID 19451621 2009 Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis.

rs11082762 in LAMA3 gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

rs2006933 in LOC101926984 gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

rs17070492 in LOC101927815 gene and Amyotrophic Lateral Sclerosis

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

rs6703183 in LOC105372898 gene and Amyotrophic Lateral Sclerosis

PMID 23624525 2013 We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, Pcombined = 2.92 × 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, Pcombined = 2.35 × 10(-9), OR = 1.52).

rs10812611 in LOC107987057;C9orf72 gene and Amyotrophic Lateral Sclerosis

PMID 23587638 2013 Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.

rs2814707 in LOC112268043;C9orf72;LOC107987057 gene and Amyotrophic Lateral Sclerosis

PMID 19734901 2009 Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.

PMID 23587638 2013 Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.

PMID 20801718 2010 Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study.

rs903603 in LOC112268043;MOB3B gene and Amyotrophic Lateral Sclerosis

PMID 20801717 2010 Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.

PMID 23587638 2013 Genome-wide association testing was performed first using all samples, and then restricting the analysis to samples not carrying the mutation. rs3849942 and rs903603 were strongly associated with ALS when all samples were included (rs3849942, p = [3 × 2] × 10(-6), rank 7/442,057; rs903603, p = [7 × 6] × 10(-8), rank 2/442,057).

rs10511816 in MOB3B gene and Amyotrophic Lateral Sclerosis

PMID 23587638 2013 Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.

PMID 20801718 2010 Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study.

PMID 25442119 2015 Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis.

rs616147 in MOBP gene and Amyotrophic Lateral Sclerosis

PMID 27455348 2016 Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

rs7638688 in NME9 gene and Amyotrophic Lateral Sclerosis

PMID 24931836 2014 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.

rs2935183 in NPEPPS gene and Amyotrophic Lateral Sclerosis

PMID 24234648 2014 No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.

rs12618157 in NRXN1 gene and Amyotrophic Lateral Sclerosis

PMID 17362836 2007 Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.

rs7477 in PIGL;CENPV gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Eight genomic regions provided evidence of association with ALS, including 9p21.2 (rs3849942, odds ratio [OR] = 1.21; p = 4.41 × 10(-7)), 17p11.2 (rs7477, OR = 1.30; p = 2.89 × 10(-7)), and 19p13 (rs12608932, OR = 1.37, p = 1.29 × 10(-7)).

PMID 24931836 2014 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.

rs4568225 in PPARGC1A gene and Amyotrophic Lateral Sclerosis

PMID 17362836 2007 Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.

rs35714695 in SARM1 gene and Amyotrophic Lateral Sclerosis

PMID 27455348 2016 Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

rs10139154 in SCFD1 gene and Amyotrophic Lateral Sclerosis

PMID 27455348 2016 Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

rs1905248 in SCN8A gene and Amyotrophic Lateral Sclerosis

PMID 17362836 2007 Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.

rs3011225 in ST3GAL3 gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

rs2303565 in STK36 gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

rs138705 in SUN2;GTPBP1 gene and Amyotrophic Lateral Sclerosis

PMID 23587638 2013 Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.

rs2708909 in SUN3 gene and Amyotrophic Lateral Sclerosis

PMID 19193627 2009 A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis.

rs8141797 in SUSD2 gene and Amyotrophic Lateral Sclerosis

PMID 23624525 2013 We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, Pcombined = 2.92 × 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, Pcombined = 2.35 × 10(-9), OR = 1.52).

rs74654358 in TBK1 gene and Amyotrophic Lateral Sclerosis

PMID 27455348 2016 Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

rs13048019 in TIAM1 gene and Amyotrophic Lateral Sclerosis

PMID 20801718 2010 Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study.

rs10463311 in TNIP1 gene and Amyotrophic Lateral Sclerosis

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

rs12608932 in UNC13A gene and Amyotrophic Lateral Sclerosis

PMID 22959728 2013 Eight genomic regions provided evidence of association with ALS, including 9p21.2 (rs3849942, odds ratio [OR] = 1.21; p = 4.41 × 10(-7)), 17p11.2 (rs7477, OR = 1.30; p = 2.89 × 10(-7)), and 19p13 (rs12608932, OR = 1.37, p = 1.29 × 10(-7)).

PMID 19734901 2009 Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.

PMID 24931836 2014 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.

PMID 24234648 2014 No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.

PMID 27455348 2016 Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

PMID 20801717 2010 Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.

PMID 29566793 2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

rs12546767 in WASHC5 gene and Amyotrophic Lateral Sclerosis

PMID 24931836 2014 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.