Gene: BCL3
Alternate names for this Gene: BCL4|D19S37
Gene Summary: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
Gene is located in Chromosome: 19
Location in Chromosome : 19q13.32
Description of this Gene: BCL3 transcription coactivator
Type of Gene: protein-coding