Gene: CABLES1
Alternate names for this Gene: CABL1|CABLES|HsT2563|IK3-1
Gene Summary: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 18
Location in Chromosome : 18q11.2
Description of this Gene: Cdk5 and Abl enzyme substrate 1
Type of Gene: protein-coding