Variant: rs281875215 

    present in Gene: CARD14
    present in Chromosome: 17
    Position on Chromosome: 80182790
    Alleles of this Variant: G/A

rs281875215 in CARD14 gene and PSORIASIS 2 PMID 27071417 2016 Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.

PMID 22521419 2012 Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.

PMID 26358359 2016 CARD14 alterations in Tunisian patients with psoriasis and further characterization in European cohorts.

PMID 22521418 2012 PSORS2 is due to mutations in CARD14.

PMID 27113748 2016 The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes.

rs281875215 in CARD14 gene and Pityriasis Rubra Pilaris PMID 27760266 2017 Pityriasis Rubra Pilaris Type V as an Autoinflammatory Disease by CARD14 Mutations.

PMID 22703878 2012 Familial pityriasis rubra pilaris is caused by mutations in CARD14.