Gene: GABBR2
Alternate names for this Gene: DEE59|EIEE59|GABABR2|GPR51|GPRC3B|HG20|HRIHFB2099|NDPLHS
Gene Summary: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Gene is located in Chromosome: 9
Location in Chromosome : 9q22.33
Description of this Gene: gamma-aminobutyric acid type B receptor subunit 2
Type of Gene: protein-coding