Gene: GRIP1

Alternate names for this Gene: FRASRS3|GRIP

Gene Summary: This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene is located in Chromosome: 12

Location in Chromosome : 12q14.3

Description of this Gene: glutamate receptor interacting protein 1

Type of Gene: protein-coding

rs7961471 in GRIP1 gene and Amyotrophic Lateral Sclerosis PMID 23624525 2013 Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.

rs10748045 in GRIP1 gene and Bipolar Disorder PMID 24964207 2014 Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.

rs1168357 in GRIP1 gene and Chronic Kidney Diseases PMID 22479191 2012 Genome-wide association and functional follow-up reveals new loci for kidney function.

rs10748045 in GRIP1 gene and Feeling suicidal (finding) PMID 24964207 2014 Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.

rs10748045 in GRIP1 gene and Major Depressive Disorder PMID 24964207 2014 Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.

rs1480011 in GRIP1 gene and Serum albumin measurement PMID 23281178 2013 A genome-wide assessment of variability in human serum metabolism.

rs147616082 in GRIP1 gene and response to bronchodilator PMID 26634245 2015 A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.