Gene: NEK10
Alternate names for this Gene: CILD44
Gene Summary:
Gene is located in Chromosome: 3
Location in Chromosome : 3p24.1
Description of this Gene: NIMA related kinase 10
Type of Gene: protein-coding
rs481519 in
NEK10 gene and
Adenocarcinoma of large intestine
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs640065 in
NEK10 gene and
Alcohol consumption
PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
rs1844983 in
NEK10 gene and
Body Height
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs1357245 in
NEK10 gene and
Breast Carcinoma
PMID 19330027 2009 Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
PMID 29059683 2017 Association analysis identifies 65 new breast cancer risk loci.
PMID 24493630 2014 A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.
rs481519 in
NEK10 gene and
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
Carcinoma of lung
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
Colorectal Carcinoma
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
Colorectal Neoplasms
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs640065 in
NEK10 gene and
Diastolic blood pressure
PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
rs481519 in
NEK10 gene and
Endometrioid carcinoma ovary
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs1357245 in
NEK10 gene and
Malignant neoplasm of breast
PMID 19330027 2009 Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.
rs481519 in
NEK10 gene and
Malignant neoplasm of large intestine
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
Malignant tumor of colon
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs640065 in
NEK10 gene and
Mean blood pressure
PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
rs481519 in
NEK10 gene and
Ovarian Serous Adenocarcinoma
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs479404 in
NEK10 gene and
Plexiform leiomyoma
PMID 30194396 2018 Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.
rs481519 in
NEK10 gene and
Prostate carcinoma
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs481519 in
NEK10 gene and
Squamous cell carcinoma of lung
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs640065 in
NEK10 gene and
Systolic Pressure
PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
rs479404 in
NEK10 gene and
Uterine Fibroids
PMID 30194396 2018 Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.
rs1388785 in
NEK10 gene and
White Blood Cell Count procedure
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs481519 in
NEK10 gene and
ovarian neoplasm
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.