Condition: ovarian neoplasm


rs12658731 in ADAMTS16 gene and ovarian neoplasm PMID 30557369 2018 Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1.

rs145022376 in ADARB2;LINC00200 gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs2363956 in ANKLE1 gene and ovarian neoplasm PMID 20852633 2010 Common variants at 19p13 are associated with susceptibility to ovarian cancer.

rs143663961 in ATAD5 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs4808075 in BABAM1;USHBP1 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

PMID 23535730 2013 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

rs185229225 in BOD1L1 gene and ovarian neoplasm PMID 27047539 2016 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence.

rs113488022 in BRAF gene and ovarian neoplasm PMID 21639808 2011 Improved survival with vemurafenib in melanoma with BRAF V600E mutation.

PMID 22608338 2012 Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.

PMID 20818844 2010 Inhibition of mutated, activated BRAF in metastatic melanoma.

PMID 21975775 2011 Epidermal growth factor receptor blockers for the treatment of ovarian cancer.

PMID 21683865 2011 Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm.

PMID 19018267 2008 KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer.

PMID 12068308 2002 Mutations of the BRAF gene in human cancer.

PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

PMID 22798288 2012 BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors.

rs1555578360 in BRCA1 gene and ovarian neoplasm PMID 15145354 2004 Nonsense-mediated mRNA decay: terminating erroneous gene expression.

rs80358010 in BRCA1;NBR2 gene and ovarian neoplasm PMID 15145354 2004 Nonsense-mediated mRNA decay: terminating erroneous gene expression.

rs11571818 in BRCA2 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

PMID 15145354 2004 Nonsense-mediated mRNA decay: terminating erroneous gene expression.

rs1057519365 in BRIP1 gene and ovarian neoplasm PMID 21964575 2011 Mutations in BRIP1 confer high risk of ovarian cancer.

PMID 27165003 2016 The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.

PMID 16116423 2005 The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J.

PMID 16153896 2005 BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.

PMID 19127258 2009 A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer.

PMID 16116424 2005 The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia.

PMID 22006311 2011 Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.

PMID 24556621 2014 Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease.

PMID 20639400 2010 Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.

PMID 26921362 2016 No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.

PMID 17033622 2006 Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.

PMID 25980754 2015 Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.

PMID 26315354 2015 Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.

PMID 25186627 2015 Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.

PMID 26681312 2016 Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.

PMID 26845104 2016 Improving performance of multigene panels for genomic analysis of cancer predisposition.

PMID 28495237 2017 Multigene panels in Ashkenazi Jewish patients yield high rates of actionable mutations in multiple non-BRCA cancer-associated genes.

PMID 26720728 2016 Inherited Mutations in Women With Ovarian Carcinoma.

PMID 24763289 2014 Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.

PMID 26689913 2015 Patterns and functional implications of rare germline variants across 12 cancer types.

PMID 26786923 2016 Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care.

PMID 27153395 2016 Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer.

PMID 25452441 2015 Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.

PMID 20159562 2010 BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.

PMID 22792074 2012 FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response.

PMID 21127055 2011 Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control.

PMID 26976419 2016 Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer.

PMID 26681682 2016 Genetic testing in a cohort of young patients with HER2-amplified breast cancer.

PMID 18628483 2008 A novel breast cancer-associated BRIP1 (FANCJ/BACH1) germ-line mutation impairs protein stability and function.

PMID 27498913 2016 Monogenic and polygenic determinants of sarcoma risk: an international genetic study.

PMID 28423363 2017 Multiple-gene panel analysis in a case series of 255 women with hereditary breast and ovarian cancer.

PMID 29368626 2018 BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer.

PMID 27443514 2016 Germline multi-gene hereditary cancer panel testing in an unselected endometrial cancer cohort.

rs1011970 in CDKN2B-AS1 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs11782652 in CHMP4C gene and ovarian neoplasm PMID 23535730 2013 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

rs7206411 in CMIP gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs58355101 in CNOT2 gene and ovarian neoplasm PMID 30557369 2018 Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1.

rs121913400 in CTNNB1 gene and ovarian neoplasm PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

rs12117623 in DNM3 gene and ovarian neoplasm PMID 30557369 2018 Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1.

rs11200014 in FGFR2 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs150303591 in FRAS1 gene and ovarian neoplasm PMID 27047539 2016 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence.

rs56084662 in FRY gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs1057941 in GBAP1 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs6456822 in GPX6 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs2072590 in HAGLR;HAGLROS gene and ovarian neoplasm PMID 20852632 2010 A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

PMID 23535730 2013 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

rs711830 in HAGLR;HOXD3 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs6755777 in HAGLROS;HAGLR gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs115392158 in HLA-B gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs7953249 in HNF1A-AS1 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs11651755 in HNF1B gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

PMID 23535730 2013 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

rs185652178 in JAKMIP2-AS1 gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs11973028 in JAZF1 gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs11119608 in KCNH1 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs112445441 in KRAS gene and ovarian neoplasm PMID 21975775 2011 Epidermal growth factor receptor blockers for the treatment of ovarian cancer.

PMID 19018267 2008 KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer.

PMID 15842656 2005 Somatic PTPN11 mutations in childhood acute myeloid leukaemia.

PMID 15696205 2005 KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib.

PMID 17332249 2007 Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations.

PMID 17910045 2008 Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia.

PMID 19047918 2009 Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia.

PMID 19358724 2009 KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay.

rs73110464 in KRT8 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs8098244 in LAMA3 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs10088218 in LINC00824 gene and ovarian neoplasm PMID 23535730 2013 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

PMID 20852632 2010 A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs1934363 in LINC02652 gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs1791890 in LOC107984393 gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs75316749 in LOC107986051 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs2665390 in LOC107986148;TIPARP gene and ovarian neoplasm PMID 20852632 2010 A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

rs10858374 in LOC107987138 gene and ovarian neoplasm PMID 30557369 2018 Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1.

rs183211 in LRRC37A2;NSF gene and ovarian neoplasm PMID 23544013 2013 Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.

rs3842595 in MGC32805;SNCAIP gene and ovarian neoplasm PMID 27047539 2016 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence.

rs2165109 in MIR4435-2HG;ACOXL gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs1243180 in MLLT10 gene and ovarian neoplasm PMID 23535730 2013 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs2974935 in MTX1 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs111478044 in NCAM2 gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs34357515 in NCLN gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs481519 in NEK10 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs169201 in NSF;LRRC37A2 gene and ovarian neoplasm PMID 23544013 2013 Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.

rs104886003 in PIK3CA gene and ovarian neoplasm PMID 22271473 2012 PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations.

PMID 15647370 2005 Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic.

PMID 20177704 2010 Alterations in p53, BRCA1, ATM, PIK3CA, and HER2 genes and their effect in modifying clinicopathological characteristics and overall survival of Bulgarian patients with breast cancer.

PMID 19671852 2009 PIK3CA mutation associates with improved outcome in breast cancer.

PMID 18371219 2008 PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer.

PMID 16353168 2006 PIK3CA mutation and histological type in breast carcinoma: high frequency of mutations in lobular carcinoma.

rs17631303 in PLEKHM1 gene and ovarian neoplasm PMID 23544013 2013 In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4 × 10(-8), HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4 × 10(-8), HR = 1.20, 95% CI: 1.17-1.38).

PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

PMID 23544013 2013 Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.

rs789336 in PRANCR gene and ovarian neoplasm PMID 30557369 2018 Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1.

rs121909224 in PTEN gene and ovarian neoplasm PMID 18767981 2009 PTEN and the PI3-kinase pathway in cancer.

PMID 11504908 2001 Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

PMID 20085938 2010 The PI3K pathway as drug target in human cancer.

rs6256 in PTH gene and ovarian neoplasm PMID 28935272 2017 Genome-wide association study evaluating single-nucleotide polymorphisms and outcomes in patients with advanced stage serous ovarian or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study.

rs9886651 in PVT1 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs11844632 in RAD51B gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs2300206 in RALY gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs8037137 in RCCD1 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs58722170 in RSPO1 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs3184504 in SH2B3;ATXN2 gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs17693104 in SH2D4B gene and ovarian neoplasm PMID 28935272 2017 Genome-wide association study evaluating single-nucleotide polymorphisms and outcomes in patients with advanced stage serous ovarian or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study.

rs7207826 in SKAP1 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

PMID 20852632 2010 A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

PMID 23535730 2013 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

rs201023017 in SLC9A9 gene and ovarian neoplasm PMID 27047539 2016 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence.

rs10069690 in TERT gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs10260419 in THSD7A gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs7651446 in TIPARP gene and ovarian neoplasm PMID 23535730 2013 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

rs6005807 in TTC28;LOC101929594 gene and ovarian neoplasm PMID 28346442 2017 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

rs11168936 in TUBA1C gene and ovarian neoplasm PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs74917072 in UBE2F;UBE2F-SCLY gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

rs59923016 in ZNF423 gene and ovarian neoplasm PMID 30898391 2019 Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.