Gene: SKAP1
Alternate names for this Gene: HEL-S-81p|SCAP1|SKAP55
Gene Summary: This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
Gene is located in Chromosome: 17
Location in Chromosome : 17q21.32
Description of this Gene: src kinase associated phosphoprotein 1
Type of Gene: protein-coding