Gene: THSD4

Alternate names for this Gene: ADAMTSL-6|ADAMTSL6|FVSY9334|PRO34005

Gene Summary:

Gene is located in Chromosome: 15

Location in Chromosome : 15q23

Description of this Gene: thrombospondin type 1 domain containing 4

Type of Gene: protein-coding

rs1441357 in THSD4 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs142200609 in THSD4 gene and Alzheimer's Disease PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.

rs12102112 in THSD4 gene and Chronic Obstructive Airway Disease PMID 30804561 2019 Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.

PMID 28166215 2017 Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

rs7180092 in THSD4 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.

rs11631778 in THSD4 gene and Diastolic blood pressure PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

rs12899618 in THSD4 gene and Forced expiratory volume function PMID 23284291 2012 Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

rs11855326 in THSD4 gene and Pulmonary function PMID 23932459 2014 Genome-wide association study of lung function phenotypes in a founder population.

PMID 20010834 2010 Genome-wide association study identifies five loci associated with lung function.

rs11855326 in THSD4 gene and Pulmonary function (finding) PMID 23932459 2014 Genome-wide association study of lung function phenotypes in a founder population.

PMID 20010834 2010 Genome-wide association study identifies five loci associated with lung function.

rs12441227 in THSD4 gene and Respiratory Function Tests PMID 23932459 2014 Genome-wide association study of lung function phenotypes in a founder population.

PMID 20010834 2010 Genome-wide association study identifies five loci associated with lung function.

PMID 23284291 2012 Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

PMID 22837378 2012 Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

rs1441357 in THSD4 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs1441358 in THSD4 gene and peak expiratory flow (procedure) PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.