Gene: TRAFD1

Alternate names for this Gene: FLN29

Gene Summary: The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009].

Gene is located in Chromosome: 12

Location in Chromosome : 12q24.13

Description of this Gene: TRAF-type zinc finger domain containing 1

Type of Gene: protein-coding

rs12231737 in TRAFD1 gene and Alanine aminotransferase measurement PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

rs12231737 in TRAFD1 gene and Aspartate aminotransferase measurement PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

rs17630235 in TRAFD1 gene and Body mass index PMID 26426971 2015 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

PMID 25673413 2015 Genetic studies of body mass index yield new insights for obesity biology.

PMID 30108127 2018 A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.

rs17630235 in TRAFD1 gene and Coronary Artery Disease PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.

rs12231737 in TRAFD1 gene and Coronary heart disease PMID 23364394 2013 A genome-wide association study of a coronary artery disease risk variant.

rs17630235 in TRAFD1 gene and Corpuscular Hemoglobin Concentration Mean PMID 23222517 2012 Seventy-five genetic loci influencing the human red blood cell.

rs17630235 in TRAFD1 gene and Diastolic blood pressure PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

rs17630235 in TRAFD1 gene and Lupus Erythematosus, Systemic PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs12231737 in TRAFD1 gene and Malignant neoplasm of esophagus PMID 21642993 2011 Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.

rs17630235 in TRAFD1 gene and Red Blood Cell Count measurement PMID 19862010 2009 Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

rs12231737 in TRAFD1 gene and Serum Alanine Aminotransferase Measurement PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

rs17630235 in TRAFD1 gene and Systolic Pressure PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.