Gene: TRPM1
Alternate names for this Gene: CSNB1C|LTRPC1|MLSN1
Gene Summary: This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants.
Gene is located in Chromosome: 15
Location in Chromosome : 15q13.3
Description of this Gene: transient receptor potential cation channel subfamily M member 1
Type of Gene: protein-coding