Variant: rs121913403 

    present in Gene: CTNNB1
    present in Chromosome: 3
    Position on Chromosome: 41224622
    Alleles of this Variant: C/A;G;T

rs121913403 in CTNNB1 gene and Adenocarcinoma of lung (disorder) PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

rs121913403 in CTNNB1 gene and Adenocarcinoma of prostate PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913403 in CTNNB1 gene and Esophageal carcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913403 in CTNNB1 gene and Gastric Adenocarcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913403 in CTNNB1 gene and Liver carcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913403 in CTNNB1 gene and Malignant Uterine Corpus Neoplasm PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913403 in CTNNB1 gene and Malignant neoplasm of ovary PMID 23188549 2013 NSGC practice guideline: risk assessment and genetic counseling for hereditary breast and ovarian cancer.

PMID 22964825 2012 Screening for ovarian cancer: U.S. Preventive Services Task Force reaffirmation recommendation statement.

PMID 19042984 2008 National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers.

rs121913403 in CTNNB1 gene and Medulloblastoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913403 in CTNNB1 gene and Pilomatrixoma PMID 11703283 2001 beta-catenin expression in pilomatrixomas. Relationship with beta-catenin gene mutations and comparison with beta-catenin expression in normal hair follicles.

PMID 12027456 2002 Identification of two novel regulated serines in the N terminus of beta-catenin.

PMID 23788249 2013 ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.

PMID 10192393 1999 A common human skin tumour is caused by activating mutations in beta-catenin.

PMID 27854360 2017 Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.

PMID 25356965 2015 ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing.

rs121913403 in CTNNB1 gene and Stomach Neoplasms PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

rs121913403 in CTNNB1 gene and Transitional cell carcinoma of bladder PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913403 in CTNNB1 gene and Uterine Cervical Neoplasm PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913403 in CTNNB1 gene and melanoma PMID 15133491 2004 Genetic and epigenetic alterations of the APC gene in malignant melanoma.

PMID 11930117 2002 Mutations in exon 3 of the beta-catenin gene are rare in melanoma cell lines.

PMID 11351304 2001 Cytoplasmic and nuclear accumulation of beta-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma.

PMID 10027390 1999 Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma.

PMID 11950921 2002 Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations.

PMID 9065403 1997 Stabilization of beta-catenin by genetic defects in melanoma cell lines.

PMID 12124804 2002 Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC.

rs121913403 in CTNNB1 gene and ovarian neoplasm PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.