present in Gene: ANKLE1
present in Chromosome: 19
Position on Chromosome: 17283315
Alleles of this Variant: T/G
rs2363956 in
ANKLE1 gene and
Malignant neoplasm of breast
PMID 20852631 2010 Genotyping these SNPs in 6,800 population-based breast cancer cases and 6,613 controls identified a similar association with estrogen receptor-negative breast cancer (rs2363956 per-allele odds ratio (OR) = 0.83, 95% CI 0.75-0.92, P(trend) = 0.0003) and an association with estrogen receptor-positive disease in the opposite direction (OR = 1.07, 95% CI 1.01-1.14, P(trend) = 0.016).
rs2363956 in
ANKLE1 gene and
Malignant neoplasm of ovary
PMID 20852633 2010 Common variants at 19p13 are associated with susceptibility to ovarian cancer.
rs2363956 in
ANKLE1 gene and
Triple Negative Breast Neoplasms
PMID 24325915 2014 Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.
rs2363956 in
ANKLE1 gene and
ovarian neoplasm
PMID 20852633 2010 Common variants at 19p13 are associated with susceptibility to ovarian cancer.