Variant: rs2363956

present in Gene: ANKLE1 present in Chromosome: 19 Position on Chromosome: 17283315 Alleles of this Variant: T/G

rs2363956 in ANKLE1 gene and Malignant neoplasm of breast PMID 20852631 2010 Genotyping these SNPs in 6,800 population-based breast cancer cases and 6,613 controls identified a similar association with estrogen receptor-negative breast cancer (rs2363956 per-allele odds ratio (OR) = 0.83, 95% CI 0.75-0.92, P(trend) = 0.0003) and an association with estrogen receptor-positive disease in the opposite direction (OR = 1.07, 95% CI 1.01-1.14, P(trend) = 0.016).

rs2363956 in ANKLE1 gene and Malignant neoplasm of ovary PMID 20852633 2010 Common variants at 19p13 are associated with susceptibility to ovarian cancer.

rs2363956 in ANKLE1 gene and Triple Negative Breast Neoplasms PMID 24325915 2014 Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.

rs2363956 in ANKLE1 gene and ovarian neoplasm PMID 20852633 2010 Common variants at 19p13 are associated with susceptibility to ovarian cancer.