present in Gene: PSRC1
present in Chromosome: 1
Position on Chromosome: 109279544
Alleles of this Variant: G/A;C
rs599839 in
PSRC1 gene and
Apolipoprotein B Assay
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
rs599839 in
PSRC1 gene and
Cerebrovascular accident
PMID 24262325 2014 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
rs599839 in
PSRC1 gene and
Coronary heart disease
PMID 17634449 2007 The combined analysis of the two studies identified four additional loci significantly associated with coronary artery disease (P<1.3x10(-6)) and a high probability (>80%) of a true association: chromosomes 1p13.3 (rs599839), 1q41 (rs17465637), 10q11.21 (rs501120), and 15q22.33 (rs17228212).
PMID 24262325 2014 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
PMID 21378990 2011 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs599839 in
PSRC1 gene and
Low density lipoprotein cholesterol measurement
PMID 18262040 2008 In our initial scan, we found two SNPs (rs599839 [p=1.7x10(-15)] and rs4970834 [p=3.0x10(-11)]) that showed genome-wide statistical association with LDL cholesterol at chromosomal locus 1p13.3.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.
rs599839 in
PSRC1 gene and
Serum LDL cholesterol measurement
PMID 18179892 2008 Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.
PMID 18262040 2008 In our initial scan, we found two SNPs (rs599839 [p=1.7x10(-15)] and rs4970834 [p=3.0x10(-11)]) that showed genome-wide statistical association with LDL cholesterol at chromosomal locus 1p13.3.
PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
rs599839 in
PSRC1 gene and
Serum albumin measurement
PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.