Condition: BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
rs587781410 in
LOC105371843;RAD51C gene and
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
PMID 22538716 2012 Germline RAD51C mutations confer susceptibility to ovarian cancer.
PMID 26681312 2016 Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
PMID 24139550 2013 Germline mutation in the RAD51B gene confers predisposition to breast cancer.
PMID 12966089 2003 Identification of functional domains in the RAD51L2 (RAD51C) protein and its requirement for gene conversion.
PMID 26057125 2015 Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic.
PMID 26822949 2016 Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
PMID 26261251 2015 Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population.
rs1060502601 in
RAD51C gene and
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
PMID 26261251 2015 Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population.
PMID 26720728 2016 Inherited Mutations in Women With Ovarian Carcinoma.
PMID 20400964 2010 Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
PMID 24141787 2014 Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
PMID 21990120 2012 Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients.
PMID 22167183 2012 Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
PMID 22451500 2012 Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families.
PMID 22538716 2012 Germline RAD51C mutations confer susceptibility to ovarian cancer.
PMID 24139550 2013 Germline mutation in the RAD51B gene confers predisposition to breast cancer.
PMID 22006311 2011 Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.
PMID 26681312 2016 Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
PMID 21537932 2011 A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families.
PMID 21750962 2011 Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility.
PMID 25086635 2014 RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families.
PMID 27913932 2017 Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene.
rs587782528 in
RAD51C;TEX14 gene and
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
PMID 26261251 2015 Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population.
PMID 26689913 2015 Patterns and functional implications of rare germline variants across 12 cancer types.
PMID 26681312 2016 Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
PMID 21616938 2011 RAD51C is a susceptibility gene for ovarian cancer.