Gene: LINGO2
Alternate names for this Gene: LERN3|LRRN6C
Gene Summary:
Gene is located in Chromosome: 9
Location in Chromosome : 9p21.2-p21.1
Description of this Gene: leucine rich repeat and Ig domain containing 2
Type of Gene: protein-coding
rs7033345 in
LINGO2 gene and
Anxiety
PMID 29942085 2018 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
rs10968749 in
LINGO2 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs10968576 in
LINGO2 gene and
Body mass index
PMID 25673413 2015 Genetic studies of body mass index yield new insights for obesity biology.
PMID 30108127 2018 A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.
PMID 26961502 2016 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
PMID 20935630 2010 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
PMID 26426971 2015 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
PMID 28448500 2017 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 28892062 2017 Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.
rs10968576 in
LINGO2 gene and
Body mass index procedure
PMID 23001569 2013 Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.
PMID 20935630 2010 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
rs7357773 in
LINGO2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs114334738 in
LINGO2 gene and
Diastolic blood pressure
PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.
rs10968576 in
LINGO2 gene and
Finding of body mass index
PMID 23001569 2013 Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.
PMID 20935630 2010 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
rs145756094 in
LINGO2 gene and
Granulocyte Colony Stimulating Factor Measurement
PMID 27989323 2017 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.
rs10968576 in
LINGO2 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs7851437 in
LINGO2 gene and
Influenza due to Influenza A virus subtype H1N1
PMID 26379185 2015 No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity.
rs56942085 in
LINGO2 gene and
Intracranial Aneurysm
PMID 30823506 2019 Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population.
rs10124164 in
LINGO2 gene and
Leukemia, Myelocytic, Acute
PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
rs10968749 in
LINGO2 gene and
Major Depressive Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs10968576 in
LINGO2 gene and
Obesity
PMID 23563607 2013 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
rs10968577 in
LINGO2 gene and
Physical Activity Measurement
PMID 28448500 2017 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
rs10812882 in
LINGO2 gene and
Schizophrenia
PMID 26198764 2015 Genome-wide association study of schizophrenia in Ashkenazi Jews.
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs10968576 in
LINGO2 gene and
Smoking
PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
PMID 26053186 2015 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
rs72724928 in
LINGO2 gene and
Smoking Behaviors
PMID 26053186 2015 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
rs10968749 in
LINGO2 gene and
Unipolar Depression
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs7870900 in
LINGO2 gene and
Vital capacity
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs10968576 in
LINGO2 gene and
Waist Circumference
PMID 25673412 2015 New genetic loci link adipose and insulin biology to body fat distribution.
rs2183825 in
LINGO2 gene and
Waist-Hip Ratio
PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
rs10968577 in
LINGO2 gene and
body fat percentage (physical finding)
PMID 30593698 2019 Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.