Variant: rs11066280 

    present in Gene: HECTD4
    present in Chromosome: 12
    Position on Chromosome: 112379979
    Alleles of this Variant: T/A

rs11066280 in HECTD4 gene and Alanine aminotransferase measurement PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.

rs11066280 in HECTD4 gene and Alcohol consumption PMID 23555315 2013 Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.

rs11066280 in HECTD4 gene and Aspartate aminotransferase measurement PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

rs11066280 in HECTD4 gene and Blood Pressure PMID 21572416 2011 Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

rs11066280 in HECTD4 gene and Coronary heart disease PMID 22751097 2012 Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.

PMID 21971053 2012 Genome-wide association study of coronary artery disease in the Japanese.

PMID 23364394 2013 A genome-wide association study of a coronary artery disease risk variant.

rs11066280 in HECTD4 gene and Diastolic blood pressure PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

PMID 26390057 2015 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

PMID 21572416 2011 Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

rs11066280 in HECTD4 gene and Drinking behavior processes PMID 23364009 2013 The association results of drinking behavior (drinkers or nondrinkers) showed a cluster of single nucleotide polymorphisms at 12q24 in discovery (P < 5 × 10(-8)), with the strongest association for rs11066280 near C12orf51 (P-combined = 3.26 × 10(-215)).

rs11066280 in HECTD4 gene and Esophageal Neoplasms PMID 21642993 2011 Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.

PMID 20833657 2010 Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.

rs11066280 in HECTD4 gene and High density lipoprotein measurement PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

rs11066280 in HECTD4 gene and Hypertensive disease PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

rs11066280 in HECTD4 gene and Major Depressive Disorder PMID 23377640 2013 Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.

rs11066280 in HECTD4 gene and Malignant neoplasm of esophagus PMID 21642993 2011 Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.

rs11066280 in HECTD4 gene and Metabolic Syndrome X PMID 25705158 2014 In the discovery phase, SNPs from chromosome 12, including rs11066280, rs2074356, and rs12229654, were associated with MetS (p < 5 × 10(-6)), and rs11066280 satisfied the Bonferroni-corrected cutoff (unadjusted p < 1.38 × 10(-7), Bonferroni-adjusted p < 0.05).

rs11066280 in HECTD4 gene and Serum Alanine Aminotransferase Measurement PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.

PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

rs11066280 in HECTD4 gene and Serum albumin measurement PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.

rs11066280 in HECTD4 gene and Systolic Pressure PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

PMID 26390057 2015 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

PMID 21572416 2011 Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

rs11066280 in HECTD4 gene and Triglycerides measurement PMID 26582766 2016 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.

rs11066280 in HECTD4 gene and Uric acid measurement (procedure) PMID 29124443 2018 Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.