Condition: Metabolic Syndrome X


rs12686004 in ABCA1 gene and Metabolic Syndrome X PMID 30382898 2018 Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs569805 in ABCB11 gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs10468017 in ALDH1A2 gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

PMID 29632305 2018 New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

rs11631342 in ALDH1A2;LIPC gene and Metabolic Syndrome X PMID 30382898 2018 Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

rs671 in ALDH2 gene and Metabolic Syndrome X PMID 28371326 2017 Notably, by an integrated analysis of the genotypes and the serum levels of APOA5, BUD13 and triglyceride, we observed that BUD13 was another potential mediator, besides APOA5, of the association between rs651821 and serum triglyceride. rs671 (ALDH2), an east Asian-specific common variant, was found to be associated with MetS (P<sub>combined</sub> = 9.7 × 10<sup>-22</sup> ) in Han Chinese.

rs651821 in APOA5 gene and Metabolic Syndrome X PMID 28371326 2017 Notably, by an integrated analysis of the genotypes and the serum levels of APOA5, BUD13 and triglyceride, we observed that BUD13 was another potential mediator, besides APOA5, of the association between rs651821 and serum triglyceride. rs671 (ALDH2), an east Asian-specific common variant, was found to be associated with MetS (P<sub>combined</sub> = 9.7 × 10<sup>-22</sup> ) in Han Chinese.

rs2075291 in APOA5;ZPR1 gene and Metabolic Syndrome X PMID 31170924 2019 Identification of female-specific genetic variants for metabolic syndrome and its component traits to improve the prediction of metabolic syndrome in females.

PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs673548 in APOB gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs9903658 in ASIC2 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs10790162 in BUD13 gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs1919128 in C2orf16 gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs1127065 in CAMK2B gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs658995 in CBLN2 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs10849915 in CCDC63 gene and Metabolic Syndrome X PMID 29632305 2018 New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

rs9939224 in CETP gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs16944558 in COLEC12 gene and Metabolic Syndrome X PMID 29212154 2017 Additionally, we found that an interaction between the <i>APOA5</i> rs662799 and <i>COLEC12</i> rs16944558 SNPs influenced MetS, high triglyceride, and low HDL.

rs8060686 in EDC4 gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs4387351 in EML3;ROM1 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs174546 in FADS1;FADS2 gene and Metabolic Syndrome X PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.

rs1535 in FADS2 gene and Metabolic Syndrome X PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.

rs10484092 in FRMD6-AS2;FRMD6 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs9940128 in FTO gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs4846922 in GALNT2 gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs3757840 in GCK gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs2293571 in GCKR gene and Metabolic Syndrome X PMID 30382898 2018 Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

PMID 29632305 2018 New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

rs3749147 in GPN1;CCDC121 gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs11066194 in HECTD4 gene and Metabolic Syndrome X PMID 30382898 2018 Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

PMID 25705158 2014 In the discovery phase, SNPs from chromosome 12, including rs11066280, rs2074356, and rs12229654, were associated with MetS (p < 5 × 10(-6)), and rs11066280 satisfied the Bonferroni-corrected cutoff (unadjusted p < 1.38 × 10(-7), Bonferroni-adjusted p < 0.05).

rs6887452 in IL17B gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs496300 in LINC01679 gene and Metabolic Syndrome X PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.

rs481843 in LINC02702 gene and Metabolic Syndrome X PMID 30382898 2018 Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

PMID 29632305 2018 New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

rs17482310 in LOC105379309 gene and Metabolic Syndrome X PMID 29632305 2018 New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

rs9987289 in LOC157273 gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs263 in LPL gene and Metabolic Syndrome X PMID 30382898 2018 Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs6439106 in MGLL gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs3099844 in MICB-DT gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs13226650 in MLXIPL gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs2361502 in MROH2A gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs3782889 in MYL2 gene and Metabolic Syndrome X PMID 29632305 2018 New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

rs10838681 in NR1H3 gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs1558162 in POU6F2;LOC105375238 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs782590 in PPP4R3B;LOC107985885 gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs10892044 in SIK3 gene and Metabolic Syndrome X PMID 30382898 2018 Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

rs560887 in SPC25;G6PC2 gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs7903146 in TCF7L2 gene and Metabolic Syndrome X PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.

rs2206277 in TFAP2B gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs102275 in TMEM258 gene and Metabolic Syndrome X PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.

rs157582 in TOMM40 gene and Metabolic Syndrome X PMID 22399527 2012 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

rs929596 in UGT1A5;UGT1A4;UGT1A9;UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A3;UGT1A1 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs12988520 in UGT1A6;UGT1A9;UGT1A8;UGT1A10;UGT1A7 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs4148325 in UGT1A8;UGT1A5;UGT1A10;UGT1A7;UGT1A1;UGT1A9;UGT1A3;UGT1A4;UGT1A6 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs2070959 in UGT1A8;UGT1A7;UGT1A9;UGT1A10;UGT1A6 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs17863787 in UGT1A9;UGT1A8;UGT1A6;UGT1A7;UGT1A10 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs13022873 in ZNF512 gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

rs892051 in ZNF98;LOC105376917 gene and Metabolic Syndrome X PMID 30621171 2019 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

rs12286037 in ZPR1 gene and Metabolic Syndrome X PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

PMID 30382898 2018 Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

PMID 22399527 2012 A previously known lipid locus, APOA1/C3/A4/A5 gene cluster region (SNP rs964184), was associated with MetS in all 4 study samples (P=7.23×10(-9) in meta-analysis).