present in Gene: FTO
present in Chromosome: 16
Position on Chromosome: 53775335
Alleles of this Variant: G/A;C
rs1121980 in
FTO gene and
Body mass index
PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
rs1121980 in
FTO gene and
Obesity
PMID 18159244 2007 Six single nucleotide polymorphisms (SNPs) in FTO (fat mass and obesity associated gene) within one linkage disequilibrium (LD) block including the GWA SNP rendering the lowest p-value (rs1121980; log-additive model: nominal p = 1.13 x 10(-7), corrected p = 0.0494; odds ratio (OR)(CT) 1.67, 95% confidence interval (CI) 1.22-2.27; OR(TT) 2.76, 95% CI 1.88-4.03) belonged to the 15 SNPs showing the strongest evidence for association with obesity.
PMID 21935397 2011 Genome-wide population-based association study of extremely overweight young adults--the GOYA study.