Condition: Calcification of coronary artery
rs4149310 in
ABCA1 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs72928364 in
ABI3BP gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs7804216 in
ACTR3C gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs1532085 in
ALDH1A2 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs16939881 in
ALDH1A2;AQP9 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs6898559 in
ALDH7A1 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs673548 in
APOB gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs445925 in
APOC1 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs74570061 in
ARL9 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs16879003 in
ATXN1 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs1004638 in
CDKN2B-AS1 gene and
Calcification of coronary artery
PMID 23394302 2013 Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
PMID 22144573 2011 Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
PMID 23727086 2013 Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort).
PMID 22144573 2011 Genome-wide significant associations with CAC for SNPs on chromosome 9p21 near CDKN2A and CDKN2B (top SNP: rs1333049; P=7.58×10(-19)) and 6p24 (top SNP: rs9349379, within the PHACTR1 gene; P=2.65×10(-11)) replicated for CAC and for MI.
PMID 23561647 2013 The 9p21 locus was significantly associated with coronary artery calcification (rs1537370, P = 2.3 × 10(-11)).
PMID 23394302 2013 The 9p21 variant, rs1537373, was most strongly associated (Beta=0.30; 95% confidence interval (CI)=0.21-0.39; p=4.05x10-11) with quantitative CAC.
rs2069418 in
CDKN2B-AS1;CDKN2B gene and
Calcification of coronary artery
PMID 22144573 2011 Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
PMID 23394302 2013 Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
rs1063192 in
CDKN2B;CDKN2B-AS1 gene and
Calcification of coronary artery
PMID 22144573 2011 Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
PMID 23394302 2013 Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
rs3809346 in
COL4A1;COL4A2 gene and
Calcification of coronary artery
PMID 22144573 2011 Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
rs10889332 in
DOCK7 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs3798722 in
ELOVL2 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs448792 in
FRY gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs6606859 in
GABRG3 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs10127775 in
GALNT2 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs1260326 in
GCKR gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs9973676 in
GPR55 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs2731672 in
GRK6 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs1912826 in
KLKB1 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs6511720 in
LDLR gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs8134546 in
LINC01426 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs749924 in
LINC01880 gene and
Calcification of coronary artery
PMID 23870195 2013 Genetics of coronary artery calcification among African Americans, a meta-analysis.
rs4788815 in
LOC105371334 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs6506900 in
LOC105372049 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs7092929 in
LOC105376360;LINC02669 gene and
Calcification of coronary artery
PMID 23870195 2013 Genetics of coronary artery calcification among African Americans, a meta-analysis.
rs9384331 in
LOC105378054 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs2390582 in
LOC105378851 gene and
Calcification of coronary artery
PMID 17903303 2007 Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.
rs10211524 in
LOC107984063;LINC02245 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs10500569 in
LOC107984814 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs115689251 in
LOC107985068 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs6754498 in
LOC107985783 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs91 in
LOC107986777 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs4841132 in
LOC157273 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs113533135 in
LRP1B gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs113805659 in
MAGI2 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs59811240 in
MTSS1 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs2306786 in
MYO1E gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs7442201 in
NSG1 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs17214144 in
OSBPL3 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs59490629 in
PDSS2 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs10807323 in
PHACTR1 gene and
Calcification of coronary artery
PMID 22144573 2011 Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
PMID 23394302 2013 The second strongest association with CAC was with rs9349379 in the phosphatase and actin regulator 1 gene, PHACTR1, (Beta=0.30; 95% CI=0.22-0.40; p=4.67x10-11).
PMID 22144573 2011 Genome-wide significant associations with CAC for SNPs on chromosome 9p21 near CDKN2A and CDKN2B (top SNP: rs1333049; P=7.58×10(-19)) and 6p24 (top SNP: rs9349379, within the PHACTR1 gene; P=2.65×10(-11)) replicated for CAC and for MI.
rs1440581 in
PPM1K-DT gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs17404667 in
PRICKLE2 gene and
Calcification of coronary artery
PMID 23870195 2013 Genetics of coronary artery calcification among African Americans, a meta-analysis.
rs4272321 in
PTPRN2 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs1303 in
SERPINA1 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs560887 in
SPC25;G6PC2 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs2657880 in
SPRYD4 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs12040333 in
ST3GAL3 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs77757620 in
STARD9 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs12051548 in
TM4SF5 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs102275 in
TMEM258 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs217181 in
TXNL4B gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
rs2680830 in
VSNL1 gene and
Calcification of coronary artery
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs964184 in
ZPR1 gene and
Calcification of coronary artery
PMID 22916037 2012 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.